Depending on what your favourite feature of a holiday, mini-break or weekend away, certain sense-simulating factors are going way beyond the aesthetic to stimulate serotonin.
Good taste Good food is a joy on so many levels.
It is quite literally a feast for the senses, whether it's something warm and comforting in the winter, or fresh and healthy in the summer.
If you are a fan of seafood however then the particularly good news is that the Vitamin D found in oily fish actually is known as a mood-booster.
Gentle touch Have you ever heard of cuddle clubs? Groups of strangers get together and pay to have a collective hug because science shows that touch makes us feel better and can also boost the white blood cells.
Well it's not like you need an excuse to head to a spa hotel, but it turns out that with that thinking in mind, having a massage is about more than getting rid of those knots, it's about all round happiness.
Sight for sore eyes It always seems incredible to us how much happiness can be generated during a walk surrounded by trees, beautiful gardens and verdant countryside.
Well, according to the chakras certain colours can really affect our mood in a positive way.
Violets and purples are optimistic but green is a bit of a whiz when it comes to feeling happy.
It is the colour of rejuvenation, it's neutral and soothing - all the things that one is generally not feeling by the time Friday afternoon comes along and you can't tell your nose from your elbow, and all the more reason to head to a country house hotel.
Sound advice Not sure about you but for most of us the day is frequently peppered with the sounds of various electronic devices pinging into action - Tweets, voicemails, text messages, emails, phone calls, and app updates galore.
It's a never-ending stream of things and people demanding attention.
It is not relaxing.
Sound doesn't have to be that way though, it can be supremely uplifting.
Think about the sound of waves crashing against the shore, a stream merrily making its way through a garden where the only other sound is birdsong.
If happiness had a sound it would definitely include a secluded waterside location like a hotel on the Isle of Skye.
Smell of de-stress Did you know that in Japan they frequently spray their factories with citrus essential oils in the mornings to boost productivity? Smell, it seems, makes a big difference to how we feel about life - lavender to relax and unwind, mandarin to soothe toddler tantrums, and citrus to remind us of the heady days of summer.
For some that might mean heading overseas to wake up to the smell of lemon groves in the morning at your chosen hotel.
For others it might mean booking a massage or taking a few essential oils with you to enjoy with a good book in a roll top bath.