Health & Medical Medications & Drugs

Inflammatory Drug Side Effects

    Common Effects

    • Common side effects of NSAIDs include: nausea, vomiting, diarrhea, constipation, decreased appetite, rash, heartburn, gas, dizziness, headache, fluid retention and drowsiness. The extent of NSAID side effects depend on age, general health, existing medical conditions and other medications you are currently taking. If these common side effects interfere with your daily activity, talk to your doctor about other NSAID options.

    Serious Side Effects

    • Serious side effects of NSAIDs include: kidney failure, liver failure, ulcers, prolonged bleeding after injury or surgery, stomach pain, swelling of feet or ankles, ringing ears, joint or muscle pain, vision changes, weakness, easy bleeding or bruising, persistent sore throat or fever, changes in amount of urine or color of urine, jaundice (yellowing of eyes or skin), black stools, persistent stomach pain or vomit resembling coffee grounds. All of these side effects can be detrimental to your health and should be addressed by a physician as soon as possible.

    Allergic Effects

    • Allergic reactions to NSAIDs are particularly dangerous because they can come on suddenly, progress quickly and result in fatality, if not treated quickly enough. If you or a loved one exhibits any of the following symptoms, seek medical attention immediately. Allergic reactions to NSAIDs include: swelling of the mouth, tongue, face, lips or throat (this may cause problems with breathing or talking), body rash, itching, swelling and dizziness.

    Drug Interactions

    • NSAIDs interact with other drugs, so inform your doctor of any other medications you are taking before using NSAIDs. Include any over-the-counter medications on your list so your doctor can consider that as well. Medications like blood thinners, arthritis drugs, diuretics, anti-ulcer medications, high blood pressure medications (ACE inhibitors or beta blockers), and diabetic medications should all be mentioned to your healthcare provider. Drug interactions may mimic other side effects, and certain combinations can be life-threatening and severely dangerous.


    • NSAIDs are a great way to control pain on a daily basis. However, because there are risks involved with taking NSAIDs, all medications should be evaluated by your physician. NSAIDs should be used with caution in pregnant women, people who frequently use alcohol, smokers, diabetics, people with asthma, heart disease, high blood pressure, liver or kidney disease, nasal polyps, lupus, stomach ulcers and bleeding problems. Your doctor may be able to suggest a different drug, in place of a NSAID, if your body is unable to withstand the side effects associated with NSAIDs.

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